题目:“Biomaterials R & D: Our Research Efforts and an Outlook into the Future”
时间:2012年5月31日(周四)下午14:30
报告人: Min Wang PhD CSci CEng
(Department of Mechanical Engineering, The University of Hong Kong)
地点:买球官网入口玉泉校区曹光彪大楼324会议室
主持: 翁文剑教授 (432办公室; 87953787)
报告摘要:
The development of modern biomaterials started more than 40 years ago. Over the past few decades, we have witnessed extensive efforts in biomaterials R & D. Some of these efforts have paid off and hence patients benefit now from new and high performance biomaterials. However, there is still much room for further explorations into better biomaterials for various applications: tissue repair, tissue regeneration, drug delivery, cancer detection and treatment, etc. There are many strategies in biomaterials R & D for improving the biomaterials currently in use and for designing and developing new biomaterials. In this seminar, some of our work in the following selected areas will be presented:
·Metallic implants provide the strength and toughness which are required in load-bearing parts of the body. However, there are concerns over ion release and corrosion products from implantable metals. Research has been conducted on forming coatings on metals using various techniques. Some coatings can produce bioactivity for metal implants, thus promoting bone formation in vivo, and at the same time limit cytotoxic ion release.
·Using natural tissues as templates, novel, “designer” biomaterials can be developed. Many non-porous bioactive ceramic-polymer composites have already been investigated for bone substitution. Particulate bioceramics (e.g., hydroxyapatite) can be incorporated into biocompatible (and biodegradable) polymers. By choosing constituent materials for composites and controlling processing parameters, the biological and mechanical performance of bioactive composites can be tailored to meet various clinical requirements.
·Tissue engineering holds the promise to solve problems of tissue loss and organ failure. One key issue in scaffold-based tissue engineering is the development of scaffolds for seeding cells and for tissue growth. There are a number of polymers for tissue engineering scaffolds and various techniques have been used to produce scaffolds. One strategy is to use industrial processes to produce good-quality bioactive nanocomposite scaffolds. These scaffolds with suitable surface modifications exhibit enhanced biological performance.
On the basis of our own biomaterials research and in the context of worldwide biomaterials R & D, an outlook will be given in areas in which we have been conducting our research work.
王敏博士简介:
Min Wang was awarded BSc and PhD (both in Materials Science and Engineering) by Shanghai Jiao Tong University and the University of London, respectively. Currently, he is a full professor at The University of Hong Kong. Dr. Wang is a Chartered Scientist (CSci) and Chartered Engineer (CEng) in the UK and has been elected fellow of professional societies in the UK, USA, Hong Kong and the world (FIMMM, 2001; FIMechE, 2007; FHKIE, 2010; FBSE, 2011; FAIMBE, 2011). His research interests include biomedical materials, tissue engineering, controlled release, and bionanotechnology. Before joining HKU in 2003, Dr. Wang conducted research and teaching in universities in the UK, Singapore and Hong Kong. He has a large number of publications in peer-reviewed journals and conference proceedings, as well as chapters on biomaterials and tissue engineering in more than 10 books. He has given many conference presentations, including more than 80 invited talks, at international conferences. He has also given more than 80 seminars in universities, research institutes and hospitals in Europe, North America, Asia and Australia. Dr. Wang has been Chairman and Organizer of many international conferences including symposia in three World Biomaterials Congresses (2004, 2008 and 2012). He has also served in the committees of more than 40 international conferences. He has been a reviewer for more than 60 international journals. Dr. Wang is the Series Editor of the Springer Series in Biomaterials Science and Engineering and also Editor or Associate Editor of several international journals. He has been an editorial board member of more than 10 other journals including Journal of the Royal Society Interface.